Phase III: Comparison
Phase III trials test how a new drug or combination of drugs, or a new surgical procedure, compares with the currently approved standard treatment. In many cases, for example, trials compare the approved, standard chemotherapy, versus standard chemotherapy plus an additional treatment. Phase III trials are randomized, meaning that women have an equal chance of being assigned to either the new therapy group or the approved treatment group. In order to prevent bias, the participant and the doctor administering the treatment may not know to which treatment group the woman has been assigned.